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- B7f75fb9f59b2e4d6216320a611b87cf2 NCIT_P378 "NCI" @default.
- B7f75fb9f59b2e4d6216320a611b87cf2 type Axiom @default.
- B7f75fb9f59b2e4d6216320a611b87cf2 annotatedProperty IAO_0000115 @default.
- B7f75fb9f59b2e4d6216320a611b87cf2 annotatedSource NCIT_C888 @default.
- B7f75fb9f59b2e4d6216320a611b87cf2 annotatedTarget "The sodium salt of levothyroxine, a synthetic levoisomer of thyroxine (T4) that is similar to the endogenous hormone produced by the thyroid gland. In peripheral tissues, levothyroxine is deiodinated by 5'-deiodinase to form triiodothyronine (T3). T3 enters the cell and binds to nuclear thyroid hormone receptors; the activated hormone-receptor complex in turn triggers gene expression and produces proteins required in the regulation of cellular respiration; thermogenesis; cellular growth and differentiation; and the metabolism of proteins, carbohydrates and lipids. T3 also exhibits cardiostimulatory effects." @default.