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- B7f8dc1c03ea7b51f0e3a9d026128ad05 NCIT_P378 "NCI" @default.
- B7f8dc1c03ea7b51f0e3a9d026128ad05 type Axiom @default.
- B7f8dc1c03ea7b51f0e3a9d026128ad05 annotatedProperty IAO_0000115 @default.
- B7f8dc1c03ea7b51f0e3a9d026128ad05 annotatedSource NCIT_C61917 @default.
- B7f8dc1c03ea7b51f0e3a9d026128ad05 annotatedTarget "A dibenzothiazepine derivative with antipsychotic property. Quetiapine fumarate antagonizes serotonin activity mediated by 5-HT 1A and 5-HT2 receptors. With a lower affinity, this agent also reversibly binds to dopamine D1 and D2 receptors in the mesolimbic and mesocortical areas of the brain leading to decreased psychotic effects, such as hallucinations and delusions. In addition, quetiapine also binds to other alpha-1, alpha-2 adrenergic and histamine H1 receptors." @default.