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- B80b19e55f18c7d9afb0eefe976a4c354 NCIT_P378 "NCI" @default.
- B80b19e55f18c7d9afb0eefe976a4c354 type Axiom @default.
- B80b19e55f18c7d9afb0eefe976a4c354 annotatedProperty IAO_0000115 @default.
- B80b19e55f18c7d9afb0eefe976a4c354 annotatedSource NCIT_C730 @default.
- B80b19e55f18c7d9afb0eefe976a4c354 annotatedTarget "The potassium salt of penicillin V, a member of the penicillin antibiotic family with broad-spectrum bactericidal activity. Penicillin V binds to and inactivates penicillin-binding proteins (PBPs), enzymes located on the inner membrane of the bacterial cell wall, resulting in the weakening of the bacterial cell wall and cell lysis. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity." @default.