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- B81b3f2f1afc6d9fd411cb6c70b6e51f6 NCIT_P378 "NCI" @default.
- B81b3f2f1afc6d9fd411cb6c70b6e51f6 type Axiom @default.
- B81b3f2f1afc6d9fd411cb6c70b6e51f6 annotatedProperty IAO_0000115 @default.
- B81b3f2f1afc6d9fd411cb6c70b6e51f6 annotatedSource NCIT_C29367 @default.
- B81b3f2f1afc6d9fd411cb6c70b6e51f6 annotatedTarget "The hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation. (NCI05)" @default.