Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B82705dd74045ea5fa5522723d5d42b0a> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B82705dd74045ea5fa5522723d5d42b0a NCIT_P378 "NCI" @default.
- B82705dd74045ea5fa5522723d5d42b0a type Axiom @default.
- B82705dd74045ea5fa5522723d5d42b0a annotatedProperty IAO_0000115 @default.
- B82705dd74045ea5fa5522723d5d42b0a annotatedSource NCIT_C61635 @default.
- B82705dd74045ea5fa5522723d5d42b0a annotatedTarget "A synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries, decreased myocardial contractility, increased blood flow and oxygen delivery to the myocardial tissue, and decreased total peripheral resistance. This agent may also modulate multi-drug resistance (MDR) activity through inhibition of the p-glycoprotein efflux pump." @default.