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- B8313326f3c3c2ee5e30c8604738ec8d6 NCIT_P378 "NCI" @default.
- B8313326f3c3c2ee5e30c8604738ec8d6 type Axiom @default.
- B8313326f3c3c2ee5e30c8604738ec8d6 annotatedProperty IAO_0000115 @default.
- B8313326f3c3c2ee5e30c8604738ec8d6 annotatedSource NCIT_C47669 @default.
- B8313326f3c3c2ee5e30c8604738ec8d6 annotatedTarget "An ethanolamine derivative with antihistaminic property. Phenyltoloxamine blocks H1 histamine receptors, thereby inhibiting phospholipase A2 and production of endothelium-derived relaxing factor, nitric oxide. Subsequent lack of activation of guanylyl cyclase through nitric oxide results in decreased cyclic GMP levels, thereby inhibiting smooth muscle constriction of various tissues, decreasing capillary permeability and decreasing other histamine-activated allergic reactions." @default.