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- B839d66fef2ec5c6e744ff8388ebeee46 NCIT_P378 "NCI" @default.
- B839d66fef2ec5c6e744ff8388ebeee46 type Axiom @default.
- B839d66fef2ec5c6e744ff8388ebeee46 annotatedProperty IAO_0000115 @default.
- B839d66fef2ec5c6e744ff8388ebeee46 annotatedSource NCIT_C394 @default.
- B839d66fef2ec5c6e744ff8388ebeee46 annotatedTarget "Any synthetic therapeutic agent which is chemically identical to or similar to the endogenous human corticotropin-releasing factor (hCRF). Synthesized in the hypothalamus, hCRF stimulates the anterior pituitary gland to secrete adrenocorticotropic hormone (ACTH). In cerebral edema, hCRF acts by impeding the flow of fluid from blood vessels into brain tissue, thereby decreasing edema and stabilizing intracranial pressure. This agent possesses anti-edema properties independent of adrenal gland function. (NCI05)" @default.