Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B84e881eceebab00a6935b73974b10ea7> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B84e881eceebab00a6935b73974b10ea7 NCIT_P378 "NCI" @default.
- B84e881eceebab00a6935b73974b10ea7 type Axiom @default.
- B84e881eceebab00a6935b73974b10ea7 annotatedProperty IAO_0000115 @default.
- B84e881eceebab00a6935b73974b10ea7 annotatedSource NCIT_C29032 @default.
- B84e881eceebab00a6935b73974b10ea7 annotatedTarget "The magnesium salt of esomeprazole, the S-isomer of omeprazole, with gastric proton pump inhibitor activity. In the acidic compartment of parietal cells, esomeprazole is protonated and converted into the active achiral sulphenamide; the active sulphenamide forms one or more covalent disulfide bonds with the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting its activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production. H+/K+ ATPase is an integral membrane protein of the gastric parietal cell." @default.