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- B868f9ed3dbfce22f86311afb8b0505b8 NCIT_P378 "NCI" @default.
- B868f9ed3dbfce22f86311afb8b0505b8 type Axiom @default.
- B868f9ed3dbfce22f86311afb8b0505b8 annotatedProperty IAO_0000115 @default.
- B868f9ed3dbfce22f86311afb8b0505b8 annotatedSource NCIT_C845 @default.
- B868f9ed3dbfce22f86311afb8b0505b8 annotatedTarget "A methylnitrosourea antineoplastic antibiotic isolated from the bacterium Streptomyces achromogenes. Streptozocin alkylates DNA, forming inter-strand DNA cross-links and inhibiting DNA synthesis. Due to its glucose moiety, this agent is readily taken up by pancreatic beta cells, inducing diabetes mellitus at high concentrations. Unlike other nitrosoureas, streptozocin causes little myelosuppression. (NCI04)" @default.