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- B87d0e3b10a31632531ed1ade6823f3c4 hasDbXref "doi:10.1016/j.cell.2018.07.028" @default.
- B87d0e3b10a31632531ed1ade6823f3c4 hasDbXref "doi:10.1101/2022.10.12.511898" @default.
- B87d0e3b10a31632531ed1ade6823f3c4 type Axiom @default.
- B87d0e3b10a31632531ed1ade6823f3c4 annotatedProperty comment @default.
- B87d0e3b10a31632531ed1ade6823f3c4 annotatedSource CL_4030057 @default.
- B87d0e3b10a31632531ed1ade6823f3c4 annotatedTarget "The term “eccentric” is used in the name eccentric medium spiny neuron (MSN) due to the exhibited transcriptional divergence from canonical spiny projection neurons. It has been noted in at least one study that an eccentric MSN differs in expression from direct and indirect MSNs by 110 genes (more than the 68 that distinguished direct and indirect spiny projection neurons from each other) and expresses many genes that have little expression in the rest of the striatum. It also has been noted in at least one human study that most eccentric MSNs expressed only DRD1, but many in the basal ganglia co-expressed DRD1 and DRD2, suggesting regional specialization of a more broadly distributed cell type." @default.