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- B87f8f36273401c3b2aa7e540ec095108 NCIT_P378 "NCI" @default.
- B87f8f36273401c3b2aa7e540ec095108 type Axiom @default.
- B87f8f36273401c3b2aa7e540ec095108 annotatedProperty IAO_0000115 @default.
- B87f8f36273401c3b2aa7e540ec095108 annotatedSource NCIT_C103823 @default.
- B87f8f36273401c3b2aa7e540ec095108 annotatedTarget "A cancer vaccine containing immunogenic, HLA-A2-specific epitopes derived from X-box-binding protein 1-unspliced (XBP1-US), XBP1-spliced (SP), syndecan-1 (CD138), and CS1 (CD2 subset 1, CRACC, SLAMF7, CD319) with potential immunomodulating and antineoplastic activities. Upon subcutaneous administration, XBP1-US/XBP1-SP/CD138/CS1 multipeptide vaccine PVX-410 may stimulate the immune system to induce a cytotoxic T-lymphocyte response against the four myeloma-specific antigens. The tumor associated antigens (TAAs) XBP1-US, XBP1-SP, CD138 and CS1, are overexpressed on the surface of multiple myeloma (MM) cells." @default.