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- B88c5d3592bae7a704dd6253d1e98da05 hasDbXref "doi:10.1016/j.cub.2021.10.015" @default.
- B88c5d3592bae7a704dd6253d1e98da05 type Axiom @default.
- B88c5d3592bae7a704dd6253d1e98da05 annotatedProperty comment @default.
- B88c5d3592bae7a704dd6253d1e98da05 annotatedSource CL_4030054 @default.
- B88c5d3592bae7a704dd6253d1e98da05 annotatedTarget "Regarding the abbreviation D1-NUDAP, NUDAP stands for "neurochemically unique domains in the accumbens and putamen". In Rhesus macaques, the RXFP1-positive interface island D1-medium spiny neuron (D1-NUDAP) has been noted to have upregulation of OPRM1 compared to DRD1-expressing medium spiny neurons located outside of the D1-exclusive island and in Islands of Calleja. Kappa-opioid receptor gene (OPRK1) has been noted to be absent from D1-NUDAP cells. Many striosome-specific markers have been noted to be upregulated in D1-NUDAP cells, including KCNIP1, KCNT1, KHDRBS3, and BACH2. PDYN, an acknowledged D1-striosome marker gene, has also been noted to be expressed in D1-NUDAPs. D1-NUDAPs also express some genes found to be selectively expressed in the matrix, including STXBP6, GDA, and SEMA3E. Gene enrichment analysis has revealed that D1-NUDAP neurons express genes that have been implicated in drug addiction and many other functions." @default.