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- B8a61e87ad457584ca60a313fe887b316 NCIT_P378 "NCI" @default.
- B8a61e87ad457584ca60a313fe887b316 type Axiom @default.
- B8a61e87ad457584ca60a313fe887b316 annotatedProperty IAO_0000115 @default.
- B8a61e87ad457584ca60a313fe887b316 annotatedSource NCIT_C562 @default.
- B8a61e87ad457584ca60a313fe887b316 annotatedTarget "A semisynthetic 4-demethoxy analogue of the antineoplastic anthracycline antibiotic daunorubicin. Idarubicin intercalates into DNA and interferes with the activity of topoisomerase II, thereby inhibiting DNA replication, RNA transcription and protein synthesis. Due to its high lipophilicity, idarubicin penetrates cell membranes more efficiently than other anthracycline antibiotic compounds." @default.