Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B8ada1403e874210299fe385926dc028f> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B8ada1403e874210299fe385926dc028f NCIT_P378 "NCI" @default.
- B8ada1403e874210299fe385926dc028f type Axiom @default.
- B8ada1403e874210299fe385926dc028f annotatedProperty IAO_0000115 @default.
- B8ada1403e874210299fe385926dc028f annotatedSource NCIT_C28958 @default.
- B8ada1403e874210299fe385926dc028f annotatedTarget "The hydrochloride salt of a diacetyl derivative of the opiate morphine, a naturally occurring alkaloid extracted from the seedpod of the Asian poppy (Papaver sp.). Once administered, diamorphine (or diacetylmorphine) is rapidly hydrolyzed to 6-monoacetylmorphine (6-MAM) and then to the end-product morphine which binds to opiate receptors located throughout the mammalian nervous and gastrointestinal systems. Inducing a potent analgesia, the use of diamoprhine is often escalated due to a tolerance effect, resulting in abuse that is associated with fatal overdose, abortion, venous sclerosis, and opportunistic infections, among other adverse effects. (NCI04)" @default.