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- B8c3dc211359a20b1c630ed1d40ca8d71 NCIT_P378 "NCI" @default.
- B8c3dc211359a20b1c630ed1d40ca8d71 type Axiom @default.
- B8c3dc211359a20b1c630ed1d40ca8d71 annotatedProperty IAO_0000115 @default.
- B8c3dc211359a20b1c630ed1d40ca8d71 annotatedSource NCIT_C20336 @default.
- B8c3dc211359a20b1c630ed1d40ca8d71 annotatedTarget "Telomeres in human cancer cells consist of a tandem array of telomeric DNA repeats bound to a specialized telomeric proteins. Telomeres allow cells to distinguish natural chromosome ends from damaged DNA. When telomere function is disrupted, a potentially lethal DNA damage response can ensue, DNA repair activities threaten the integrity of chromosome ends, and extensive genome instability can arise. Both telomerase and recombination can lengthen telomeres. (from PMID 11850780 and NCI)" @default.