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- B8c43e9422ce6276947c25a3a62d26043 NCIT_P378 "NCI" @default.
- B8c43e9422ce6276947c25a3a62d26043 type Axiom @default.
- B8c43e9422ce6276947c25a3a62d26043 annotatedProperty IAO_0000115 @default.
- B8c43e9422ce6276947c25a3a62d26043 annotatedSource NCIT_C1560 @default.
- B8c43e9422ce6276947c25a3a62d26043 annotatedTarget "A synthetic quinolinecarboxylic acid analogue with antineoplastic properties. Brequinar inhibits the enzyme dihydroorotate dehydrogenase, thereby blocking de novo pyrimidine biosynthesis. This agent may also enhance the in vivo antitumor effect of antineoplastic agents such as 5-FU. (NCI04)" @default.