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- B8cfe6d5277b52c696ce3cc9791dee6fa NCIT_P378 "NCI" @default.
- B8cfe6d5277b52c696ce3cc9791dee6fa type Axiom @default.
- B8cfe6d5277b52c696ce3cc9791dee6fa annotatedProperty IAO_0000115 @default.
- B8cfe6d5277b52c696ce3cc9791dee6fa annotatedSource NCIT_C76136 @default.
- B8cfe6d5277b52c696ce3cc9791dee6fa annotatedTarget "A bisquaternary ammonium alcohol with parasympathomimetic activity. The positive charge of ambenonium allows it to act as an acetylcholinesterase inhibitor by binding to the anionic site at the reactive center of acetylcholinesterase, preventing the breakdown of acetylcholine and producing an indirect cholinomimetic effect at both nicotinic and muscarinic receptors. Ambenonium also has direct agonist activity at nicotinic receptors, potentiating the cholinomimetic effect at the neuromuscular junction." @default.