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- B8e53ae70bbe7d5d17ebce32a0315b4b3 hasDbXref "NCIT:C2915" @default.
- B8e53ae70bbe7d5d17ebce32a0315b4b3 type Axiom @default.
- B8e53ae70bbe7d5d17ebce32a0315b4b3 annotatedProperty IAO_0000115 @default.
- B8e53ae70bbe7d5d17ebce32a0315b4b3 annotatedSource MONDO_0005369 @default.
- B8e53ae70bbe7d5d17ebce32a0315b4b3 annotatedTarget "A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement." @default.