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- B8fc8af73ac040d4fadcfb37958ec8aad NCIT_P378 "NCI" @default.
- B8fc8af73ac040d4fadcfb37958ec8aad type Axiom @default.
- B8fc8af73ac040d4fadcfb37958ec8aad annotatedProperty IAO_0000115 @default.
- B8fc8af73ac040d4fadcfb37958ec8aad annotatedSource NCIT_C129596 @default.
- B8fc8af73ac040d4fadcfb37958ec8aad annotatedTarget "A therapeutic peptide vaccine containing the human telomerase reverse transcriptase catalytic subunit (hTERT)-derived universal cancer peptides 2 (UCP2) and 4 (UCP4), and combined with the immunoadjuvant Montanide ISA 51 VG, with potential immunostimulating and antineoplastic activities. Vaccination with the CD4-specific telomerase peptide vaccine UCPVax activates the immune system to mount a T-helper 1 (TH1) CD4-positive T-lymphocyte immune response against and ultimately killing telomerase-expressing cells. Telomerase, a reverse transcriptase normally repressed in healthy cells, is overexpressed in most cancer cells and plays a key role in cellular proliferation." @default.