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- B8fe699f2c5b6e2ed2663aa5eedf28348 NCIT_P378 "NCI" @default.
- B8fe699f2c5b6e2ed2663aa5eedf28348 type Axiom @default.
- B8fe699f2c5b6e2ed2663aa5eedf28348 annotatedProperty IAO_0000115 @default.
- B8fe699f2c5b6e2ed2663aa5eedf28348 annotatedSource NCIT_C47667 @default.
- B8fe699f2c5b6e2ed2663aa5eedf28348 annotatedTarget "A phenylalkylamine sympathomimetic amine with appetite depressant property. Phendimetrazine tartrate is a prodrug that is hydrolyzed to the active metabolite phenmetrazine, which competes with norepinephrine and dopamine for their presynaptic transporters, thereby blocks the reuptake of these monoamines at the neuronal junctions. As a result, this prolongs activities of dopamine and norepinephrine and leads to central nervous system (CNS) stimulation and metabolic effects, including appetite-suppression, decreased gastric acid secretion and increased blood pressure." @default.