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- B9058e27c1323530490d2fa193521d55a NCIT_P378 "NCI" @default.
- B9058e27c1323530490d2fa193521d55a type Axiom @default.
- B9058e27c1323530490d2fa193521d55a annotatedProperty IAO_0000115 @default.
- B9058e27c1323530490d2fa193521d55a annotatedSource NCIT_C1574 @default.
- B9058e27c1323530490d2fa193521d55a annotatedTarget "An orally- and topically-active naturally-occurring retinoic acid with antineoplastic, chemopreventive, teratogenic, and embryotoxic activities. Alitretinoin binds to and activates nuclear retinoic acid receptors (RAR) and retinoid X receptors (RXR); these activated receptors act as transcription factors, regulating gene expression that results in the inhibition of cell proliferation, induction of cell differentiation, and apoptosis of both normal cells and tumor cells." @default.