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- B90a8f572329bbd4b19144886aefc854a NCIT_P378 "NCI" @default.
- B90a8f572329bbd4b19144886aefc854a type Axiom @default.
- B90a8f572329bbd4b19144886aefc854a annotatedProperty IAO_0000115 @default.
- B90a8f572329bbd4b19144886aefc854a annotatedSource NCIT_C495 @default.
- B90a8f572329bbd4b19144886aefc854a annotatedTarget "A recombinant protein which is chemically identical to or similar to endogenous interferon beta with antiviral and anti-tumor activities. Endogenous interferons beta are cytokines produced by nucleated cells (predominantly natural killer cells) upon exposure to live or inactivated virus, double-stranded RNA or bacterial products. These agents bind to specific cell-surface receptors, resulting in the transcription and translation of genes with an interferon-specific response element. The proteins so produced mediate many complex effects, including antiviral (the most important being inhibition of viral protein synthesis), antiproliferative and immune modulating effects. The recombinant therapeutic forms of interferon beta are interferon beta 1-a and interferon beta 1-b. (NCI05)" @default.