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- B90addbc82812c139036d0c83b75c47f6 NCIT_P378 "NCI" @default.
- B90addbc82812c139036d0c83b75c47f6 type Axiom @default.
- B90addbc82812c139036d0c83b75c47f6 annotatedProperty IAO_0000115 @default.
- B90addbc82812c139036d0c83b75c47f6 annotatedSource NCIT_C72699 @default.
- B90addbc82812c139036d0c83b75c47f6 annotatedTarget "The hydrochloride salt form of amotosalen, a synthetic psoralen and light-activated DNA, RNA crosslinking agent, with protective activity against pathogens such as bacteria, viruses, protozoa, and leukocytes. Prior to administration amotosalen is added to plasma and platelets, then in vivo the agent penetrates pathogens and targets DNA and RNA. Upon activation by ultraviolet A light, this agent is able to form interstrand DNA and RNA crosslinks and prevents replication. Inactivation of leukocytes can prevent graft versus host disease upon transfusion." @default.