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- B90b32349e4ed84d3886b540a7798bd37 NCIT_P378 "NCI" @default.
- B90b32349e4ed84d3886b540a7798bd37 type Axiom @default.
- B90b32349e4ed84d3886b540a7798bd37 annotatedProperty IAO_0000115 @default.
- B90b32349e4ed84d3886b540a7798bd37 annotatedSource NCIT_C98086 @default.
- B90b32349e4ed84d3886b540a7798bd37 annotatedTarget "Any inhibitor of the proline-specific serine protease dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. DPP-4 inhibitors bind to DPP-4 and inhibit the breakdown of the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). This prolongs incretin activity, increases postprandial insulin release, decreases glucagon release, delays gastric emptying and lowers blood glucose levels. The risk for hypoglycemia is negligible with the use of DPP-4 inhibitors." @default.