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- B9151bb100262c7547ad0f286b4d51ce0 hasDbXref "PMID:23616747" @default.
- B9151bb100262c7547ad0f286b4d51ce0 type Axiom @default.
- B9151bb100262c7547ad0f286b4d51ce0 annotatedProperty comment @default.
- B9151bb100262c7547ad0f286b4d51ce0 annotatedSource CL_0000129 @default.
- B9151bb100262c7547ad0f286b4d51ce0 annotatedTarget "Unlike macroglial cells, microglial cells arise from hematopoietic stem cells in the yolk sac during early embryogenesis that populate the central nervous system. They derive from embryonic mesoderm and are not from neuroectoderm where glioblast develops from. Markers: Mouse: CD11b+, F4/80+, CD68+. They represent ~12% of the cells in the CNS, but they are not uniformly distributed within the CNS. A normal adult mouse brain has approximately 3.5x10e6 microglia. Microglia are also reportedly CD3-negative, CD4-positive, CD8-negative, CD11b-positive, CD11c-high, CD14-negative, CD19-negative, CD45-low, CD56-negative, CD163-negative, CD200R-positive, CD281-positive, CD282-positive, CD283-positive, CD284-positive, CD285-positive, CD286-positive, CD287-positive, CD288-positive, CD289-positive, Gr1-negative, nestin-positive, and PU.1-positive." @default.