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- B91d1692232ddea1530935e134423ef8f hasDbXref "Orphanet:518" @default.
- B91d1692232ddea1530935e134423ef8f type Axiom @default.
- B91d1692232ddea1530935e134423ef8f annotatedProperty IAO_0000115 @default.
- B91d1692232ddea1530935e134423ef8f annotatedSource MONDO_0018872 @default.
- B91d1692232ddea1530935e134423ef8f annotatedTarget "Acute megakaryoblastic leukemia (AMKL) is a form of acute myeloid leukemia (AML) that occurs predominantly in childhood and particularly in children with Down syndrome (DS-AMKL). Nonspecific symptoms may be irritability, weakness, and dizziness while specific symptoms include pallor, fever, mucocutaneous bleeding, hepatosplenomegaly, neurological manifestations and rarely lymphadenopathy. Acute panmyelosis with myelofibrosis may also be associated with AMKL. In contrast to DS-AMKL (around 80 % survival), non-DS-AMKL is an AML subgroup associated with poor prognosis." @default.