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- B932975e17a6cee359362bcd0fe071e02 NCIT_P378 "NCI" @default.
- B932975e17a6cee359362bcd0fe071e02 type Axiom @default.
- B932975e17a6cee359362bcd0fe071e02 annotatedProperty IAO_0000115 @default.
- B932975e17a6cee359362bcd0fe071e02 annotatedSource NCIT_C2564 @default.
- B932975e17a6cee359362bcd0fe071e02 annotatedTarget "The sodium form of allopurinol, which is a structural isomer of hypoxanthine. Allopurinol inhibits xanthine oxidase, an enzyme that converts oxypurines to uric acid. By blocking the production of uric acid, this agent decreases serum and urine concentrations of uric acid, thereby providing protection against uric acid-mediated end organ damage in conditions associated with excessive production of uric acid, i.e. the massive cell lysis associated with the treatment of some malignancies. (NCI04)" @default.