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- B942bb9e5c8e862f7b7437f1ac2a38f63 NCIT_P378 "NCI" @default.
- B942bb9e5c8e862f7b7437f1ac2a38f63 type Axiom @default.
- B942bb9e5c8e862f7b7437f1ac2a38f63 annotatedProperty IAO_0000115 @default.
- B942bb9e5c8e862f7b7437f1ac2a38f63 annotatedSource NCIT_C104267 @default.
- B942bb9e5c8e862f7b7437f1ac2a38f63 annotatedTarget "An orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. Derazantinib binds to and potently inhibits the activity of FGFR subtypes 1, 2 and 3. This may result in the inhibition of FGFR-mediated signal transduction pathways, tumor cell proliferation, tumor angiogenesis and tumor cell death in FGFR-overexpressing tumor cells. FGFR, a receptor tyrosine kinase, is upregulated in many tumor cell types and plays a key role in tumor cellular proliferation, differentiation, angiogenesis and survival." @default.