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- B94fc7298e70101db5a267701c219048c NCIT_P378 "NCI" @default.
- B94fc7298e70101db5a267701c219048c type Axiom @default.
- B94fc7298e70101db5a267701c219048c annotatedProperty IAO_0000115 @default.
- B94fc7298e70101db5a267701c219048c annotatedSource NCIT_C479 @default.
- B94fc7298e70101db5a267701c219048c annotatedTarget "A synthetic molecule combining estradiol and nornitrogen mustard through a carbamate link. Estramustine and its major metabolite estramustine bind to microtubule-associated proteins (MAPs) and tubulin, thereby inhibiting microtubule dynamics and leading to anaphase arrest in a dose-dependent fashion. This agent also exhibits anti-androgenic effects. (NCI04)" @default.