Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B9616ffe4681deba0e794e805d4874e0d> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B9616ffe4681deba0e794e805d4874e0d NCIT_P378 "NCI" @default.
- B9616ffe4681deba0e794e805d4874e0d type Axiom @default.
- B9616ffe4681deba0e794e805d4874e0d annotatedProperty IAO_0000115 @default.
- B9616ffe4681deba0e794e805d4874e0d annotatedSource NCIT_C166377 @default.
- B9616ffe4681deba0e794e805d4874e0d annotatedTarget "A synthetic form of the plant-derived medicinal agent, plumbagin, with potential antineoplastic activity. Plumbagin may act by inhibiting the expression of protein kinase C epsilon (PKCe), signal transducers and activators of transcription 3 phosphorylation (Stat3), protein kinase B (AKT), and certain epithelial-to-mesenchymal transition (EMT) markers, including vimentin and slug. This results in possible inhibition of proliferation in susceptible tumor cells. PKCe, Stat3, AKT, and the EMT markers vimentin and slug have been linked to the induction and progression of prostate cancer." @default.