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- B961c6daeb4bc0562962a9b48c7383244 NCIT_P378 "NCI" @default.
- B961c6daeb4bc0562962a9b48c7383244 type Axiom @default.
- B961c6daeb4bc0562962a9b48c7383244 annotatedProperty IAO_0000115 @default.
- B961c6daeb4bc0562962a9b48c7383244 annotatedSource NCIT_C192 @default.
- B961c6daeb4bc0562962a9b48c7383244 annotatedTarget "A sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion. (NCI04)" @default.