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- B98ab3ebe3ed52f828ded90946efeed2c NCIT_P378 "NCI" @default.
- B98ab3ebe3ed52f828ded90946efeed2c type Axiom @default.
- B98ab3ebe3ed52f828ded90946efeed2c annotatedProperty IAO_0000115 @default.
- B98ab3ebe3ed52f828ded90946efeed2c annotatedSource NCIT_C65224 @default.
- B98ab3ebe3ed52f828ded90946efeed2c annotatedTarget "A sulfonamide triptan with extracerebral, intracranial vasoconstrictor activity. Almotriptan selectively binds to and activates serotonin 5-HT 1B and 1D receptors in the central nervous system (CNS), thereby causing extracerebral, intracranial blood vessel constriction. This may lead to pain relief from vascular headaches. Almotriptan may also relieve vascular headaches by preventing the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater during a migraine, by reducing extravasation of plasma proteins, and by decreasing the release of other mediators of inflammation from the trigeminal nerve." @default.