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- B9c226e7d3f957861b436d76332af5e3f NCIT_P378 "NCI" @default.
- B9c226e7d3f957861b436d76332af5e3f type Axiom @default.
- B9c226e7d3f957861b436d76332af5e3f annotatedProperty IAO_0000115 @default.
- B9c226e7d3f957861b436d76332af5e3f annotatedSource NCIT_C61735 @default.
- B9c226e7d3f957861b436d76332af5e3f annotatedTarget "An indole derivative and a potent serotonin 5-HT3 receptor antagonist with anti-emetic property. Dolasetron blocks the activity of serotonin released from the enterochromaffin cells of the small intestine by selectively inhibiting and inactivating 5-HT3 receptors located on the nerve terminals of the vagus nerve in the periphery and centrally in the chemoreceptor trigger zone of the area postrema. This results in suppression of signalling to trigger chemo- and radiotherapy induced nausea and vomiting." @default.