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- B9c6abfaad5696d108ab672d174e8a3d0 NCIT_P378 "NCI" @default.
- B9c6abfaad5696d108ab672d174e8a3d0 type Axiom @default.
- B9c6abfaad5696d108ab672d174e8a3d0 annotatedProperty IAO_0000115 @default.
- B9c6abfaad5696d108ab672d174e8a3d0 annotatedSource NCIT_C215 @default.
- B9c6abfaad5696d108ab672d174e8a3d0 annotatedTarget "A racemic mixture of the r-isomer levalbuterol and s-albuterol, a short-acting sympathomimetic agent with bronchodilator activity. Albuterol stimulates beta-2 adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. Albuterol although to a lesser extent, also stimulates beta-1 adrenergic receptors, thereby increasing the force and rate of myocardial contraction." @default.