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- B9c8b7f364aefe432fb1a28252871e409 NCIT_P378 "NCI" @default.
- B9c8b7f364aefe432fb1a28252871e409 type Axiom @default.
- B9c8b7f364aefe432fb1a28252871e409 annotatedProperty IAO_0000115 @default.
- B9c8b7f364aefe432fb1a28252871e409 annotatedSource NCIT_C49091 @default.
- B9c8b7f364aefe432fb1a28252871e409 annotatedTarget "A small molecule compound with potential antineoplastic activities. BI 2536 binds to and inhibits Polo-like kinase 1 (Plk1), resulting in mitotic arrest, disruption of cytokinesis, and apoptosis in susceptible tumor cell populations. Plk1, a serine/threonine-protein kinase, is a key regulator of multiple processes fundamental to mitosis and cell division." @default.