Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B9d1614f2fd2086e5145eb9fb8d9e38ae> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B9d1614f2fd2086e5145eb9fb8d9e38ae NCIT_P378 "NCI" @default.
- B9d1614f2fd2086e5145eb9fb8d9e38ae type Axiom @default.
- B9d1614f2fd2086e5145eb9fb8d9e38ae annotatedProperty IAO_0000115 @default.
- B9d1614f2fd2086e5145eb9fb8d9e38ae annotatedSource NCIT_C853 @default.
- B9d1614f2fd2086e5145eb9fb8d9e38ae annotatedTarget "A polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and tumor growth factor-beta (TGF-beta), to their receptors, thereby inhibiting endothelial cell proliferation and migration. This agent also inhibits vascular endothelial growth factor (VEGF)- and basic fibroblast growth factor (bFGF)-induced angiogenesis; retroviral reverse transcriptase; uncoupling of G-proteins from receptors; topoisomerases; cellular folate transport; and steroidogenesis. (NCI04)" @default.