Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/B9d5dbb3f757f2d04f7ff1aa0386ff63e> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- B9d5dbb3f757f2d04f7ff1aa0386ff63e NCIT_P378 "NCI" @default.
- B9d5dbb3f757f2d04f7ff1aa0386ff63e type Axiom @default.
- B9d5dbb3f757f2d04f7ff1aa0386ff63e annotatedProperty IAO_0000115 @default.
- B9d5dbb3f757f2d04f7ff1aa0386ff63e annotatedSource NCIT_C48000 @default.
- B9d5dbb3f757f2d04f7ff1aa0386ff63e annotatedTarget "The hydrochloride salt form of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. Lidocaine interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation. Lidocaine hydrochloride also exhibits class IB antiarrhythmic effects. The agent decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability." @default.