Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Ba02246c75d0161607845cf8786cf25d6> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- Ba02246c75d0161607845cf8786cf25d6 NCIT_P378 "NCI" @default.
- Ba02246c75d0161607845cf8786cf25d6 type Axiom @default.
- Ba02246c75d0161607845cf8786cf25d6 annotatedProperty IAO_0000115 @default.
- Ba02246c75d0161607845cf8786cf25d6 annotatedSource NCIT_C104737 @default.
- Ba02246c75d0161607845cf8786cf25d6 annotatedTarget "A synthetic peptide vaccine consisting of a HLA-DRw53-restricted human Wilms' Tumor protein-1 (WT1) peptide comprised of amino acids 247 through 261, a HLA class II-restricted WT1 peptide, with potential immunomodulating and antitumor activities. Vaccination with WT1 247-261 peptide may stimulate a CD4-positive helper T-lymphocyte-mediated immune response against WT1 expressing cells. Activated helper T-cells stimulate dendritic cells, and activate the proliferation of other T-lymphoctes and B-lymphocytes. This causes tumor cell lysis and inhibition of cancer cell proliferation in WT1-overexpressing tumor cells. WT1, a zinc finger DNA-binding protein, is overexpressed in most types of leukemia and in a variety of solid cancers." @default.