Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Ba080af976736a3e684fa60d37c3b517f> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- Ba080af976736a3e684fa60d37c3b517f NCIT_P378 "NCI" @default.
- Ba080af976736a3e684fa60d37c3b517f type Axiom @default.
- Ba080af976736a3e684fa60d37c3b517f annotatedProperty IAO_0000115 @default.
- Ba080af976736a3e684fa60d37c3b517f annotatedSource NCIT_C82371 @default.
- Ba080af976736a3e684fa60d37c3b517f annotatedTarget "A whole, heat-killed, recombinant Saccharomyces cerevisiae yeast-based vaccine genetically altered to express the carcinoembryonic antigen (CEA) peptide 610D with potential immunostimulating and antineoplastic activities. Upon administration, recombinant Saccharomyces cerevisia-CEA(610D) vaccine GI-6207 may stimulate a host cytotoxic T-lymphocyte (CTL) response against CEA-expressing tumor cells, which may result in tumor cell lysis. CEA, a tumor associated antigen, is overexpressed on a wide variety of human cancer cells including colorectal, gastric, lung, breast and pancreatic cancer cells. CEA 610D encodes for 9 amino acids (605-613) in which aspartate is substituted for asparagine at position 610 (610D) in order to strengthen the induction of the CTL response against CEA-expressing tumor cells." @default.