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- Ba23ecf9ee62ed5f7b05483949f3cd3f1 NCIT_P378 "NCI" @default.
- Ba23ecf9ee62ed5f7b05483949f3cd3f1 type Axiom @default.
- Ba23ecf9ee62ed5f7b05483949f3cd3f1 annotatedProperty IAO_0000115 @default.
- Ba23ecf9ee62ed5f7b05483949f3cd3f1 annotatedSource NCIT_C1099 @default.
- Ba23ecf9ee62ed5f7b05483949f3cd3f1 annotatedTarget "A synthetic 4-azasteroid compound. Finasteride competitively binds to and inhibits steroid type II 5-alpha-reductase in the prostate gland, liver, and skin, thereby interfering with the enzymatic conversion of testosterone to 5-dihydrotestosterone (DHT) and reducing serum DHT levels. The reduction in serum DHT levels results in diminished stimulation of androgen receptors in the nuclei of prostate cells and, so, diminished prostate cell proliferation." @default.