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- Ba2c7d64f21d9d15c352e04f1d90167f1 NCIT_P378 "NCI" @default.
- Ba2c7d64f21d9d15c352e04f1d90167f1 type Axiom @default.
- Ba2c7d64f21d9d15c352e04f1d90167f1 annotatedProperty IAO_0000115 @default.
- Ba2c7d64f21d9d15c352e04f1d90167f1 annotatedSource NCIT_C123927 @default.
- Ba2c7d64f21d9d15c352e04f1d90167f1 annotatedTarget "A long-acting, engineered and pegylated version of human granulocyte-colony stimulating factor (G-CSF), with potential hematopoietic activity. Similar to G-CSF, pegfilgrastim anti-neutropenic factor (ANF) binds to and activates specific cell surface receptors, and stimulates neutrophil progenitor proliferation and differentiation. Therefore, this agent may prevent the duration and incidence of chemotherapy-induced neutropenia. Compared to filgrastim, the conjugation with a branched polyethylene glycol molecule reduces renal clearance and increases its plasma half-life." @default.