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- Ba43099d5e9ac2ad97099b9a5fd0de8c6 NCIT_P378 "NCI" @default.
- Ba43099d5e9ac2ad97099b9a5fd0de8c6 type Axiom @default.
- Ba43099d5e9ac2ad97099b9a5fd0de8c6 annotatedProperty IAO_0000115 @default.
- Ba43099d5e9ac2ad97099b9a5fd0de8c6 annotatedSource NCIT_C80089 @default.
- Ba43099d5e9ac2ad97099b9a5fd0de8c6 annotatedTarget "A synthetic 9-amino-anthracycline with antineoplastic activity. Amrubicin intercalates into DNA and inhibits the activity of topoisomerase II, resulting in inhibition of DNA replication, and RNA and protein synthesis, followed by cell growth inhibition and cell death. This agent has demonstrated a higher level of anti-tumor activity than conventional anthracycline drugs without exhibiting any indication of the cumulative cardiac toxicity common to this class of compounds." @default.