Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Ba5694dcffb95e4cd93ad2dbeea0ed9b2> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- Ba5694dcffb95e4cd93ad2dbeea0ed9b2 NCIT_P378 "NCI" @default.
- Ba5694dcffb95e4cd93ad2dbeea0ed9b2 type Axiom @default.
- Ba5694dcffb95e4cd93ad2dbeea0ed9b2 annotatedProperty IAO_0000115 @default.
- Ba5694dcffb95e4cd93ad2dbeea0ed9b2 annotatedSource NCIT_C97555 @default.
- Ba5694dcffb95e4cd93ad2dbeea0ed9b2 annotatedTarget "The sodium salt of leucovorin, an active metabolite of folic acid, used as an antidote to folic acid antagonists. Leucovorin does not require metabolism by dihydrofolate reductase, the molecular target of folate antagonists and counteracts the toxic effects of these drugs. This agent also potentiates the effects of fluorouracil and its derivatives by stabilizing the binding of the drug's metabolite to its target enzyme, thus prolonging drug activity. In comparison with the calcium salt, sodium salt does not form precipitate when mixed other folate antagonists." @default.