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- Ba59cf0b276f7be249ccc1cc9c445345f NCIT_P378 "NCI" @default.
- Ba59cf0b276f7be249ccc1cc9c445345f type Axiom @default.
- Ba59cf0b276f7be249ccc1cc9c445345f annotatedProperty IAO_0000115 @default.
- Ba59cf0b276f7be249ccc1cc9c445345f annotatedSource NCIT_C1862 @default.
- Ba59cf0b276f7be249ccc1cc9c445345f annotatedTarget "A poorly adsorbed analog of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. (NCI)" @default.