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- Ba5c192835370a929a84e8b617be237f3 NCIT_P378 "NCI" @default.
- Ba5c192835370a929a84e8b617be237f3 type Axiom @default.
- Ba5c192835370a929a84e8b617be237f3 annotatedProperty IAO_0000115 @default.
- Ba5c192835370a929a84e8b617be237f3 annotatedSource NCIT_C61733 @default.
- Ba5c192835370a929a84e8b617be237f3 annotatedTarget "A synthetic catecholamine with sympathomimetic activity. Dobutamine is a direct-acting inotropic agent and an adrenergic agonist that stimulates primarily the beta-1 adrenoceptor, with lesser effect on beta-2 or alpha receptors. Via beta-1 adrenoceptor of the heart, this agent induces positive inotropic effect with minimal changes in chronotropic activities or systemic vascular resistance. Dobutamine also causes vasodilation by stimulating beta-2 adrenergic receptors in blood vessels, augmented by reflex vasoconstriction resulting in increased cardiac output." @default.