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- Ba816d57f5802d74036b60a6200d6992c NCIT_P378 "NCI" @default.
- Ba816d57f5802d74036b60a6200d6992c type Axiom @default.
- Ba816d57f5802d74036b60a6200d6992c annotatedProperty IAO_0000115 @default.
- Ba816d57f5802d74036b60a6200d6992c annotatedSource NCIT_C180598 @default.
- Ba816d57f5802d74036b60a6200d6992c annotatedTarget "A preparation of autologous T-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) human epidermal growth factor receptor 2 (HER2; ErbB2; HER-2), with potential immunostimulating and antineoplastic activities. Upon administration, autologous anti-HER2 CAR-T cells target and bind to HER2-expressing tumor cells, thereby inducing selective toxicity in HER2-expressing tumor cells. HER2 is overexpressed in a variety of cancer cell types and is associated with increased tumor cell proliferation." @default.