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- Ba8c7331f6672921f7dcb0fd7cfa99bff NCIT_P378 "NCI" @default.
- Ba8c7331f6672921f7dcb0fd7cfa99bff type Axiom @default.
- Ba8c7331f6672921f7dcb0fd7cfa99bff annotatedProperty IAO_0000115 @default.
- Ba8c7331f6672921f7dcb0fd7cfa99bff annotatedSource NCIT_C2641 @default.
- Ba8c7331f6672921f7dcb0fd7cfa99bff annotatedTarget "The hydrochloride salt of a modified glutathione analogue with potential antineoplastic activity. Canfosfamide is selectively activated by glutathione S-transferase P1-1 into an alkylating metabolite that forms covalent linkages with nucleophilic centers in tumor cell DNA, which may induce a cellular stress response and cytotoxicity, and decrease tumor proliferation. S-transferase P1-1 is an enzyme that is overexpressed in many human malignancies." @default.