Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Ba91d3f2c3c273a92861b5f0f0efe05c9> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- Ba91d3f2c3c273a92861b5f0f0efe05c9 NCIT_P378 "NCI" @default.
- Ba91d3f2c3c273a92861b5f0f0efe05c9 type Axiom @default.
- Ba91d3f2c3c273a92861b5f0f0efe05c9 annotatedProperty IAO_0000115 @default.
- Ba91d3f2c3c273a92861b5f0f0efe05c9 annotatedSource NCIT_C91708 @default.
- Ba91d3f2c3c273a92861b5f0f0efe05c9 annotatedTarget "A formulation composed of DOTAP:cholesterol liposomal nanoparticles complexed with a plasmid expression cassette encoding human FUS1 protein, with potential antineoplastic activity. Upon administration, DOTAP:chol-Fus1 liposome complex accumulates mainly in the lungs and particularly in cancer cells. Upon transfer of the Fus1 gene into tumor cells, the expression of Fus1 may induce tumor cell apoptosis and suppress tumor cell proliferation. Fus1, a potent tumor-suppressor protein, is present in normal, healthy cells but often absent in certain cancer cells. DOTAP:cholesterol liposome is composed of cationic lipid dioleoyl-trimethylammonium propane (DOTAP) and cholesterol at a molar ratio of 1:1." @default.