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- Babe03294e46c289ae6b19824f7dc9677 NCIT_P378 "NCI" @default.
- Babe03294e46c289ae6b19824f7dc9677 type Axiom @default.
- Babe03294e46c289ae6b19824f7dc9677 annotatedProperty IAO_0000115 @default.
- Babe03294e46c289ae6b19824f7dc9677 annotatedSource NCIT_C295 @default.
- Babe03294e46c289ae6b19824f7dc9677 annotatedTarget "A complex of cyclic polypeptide antibiotics, mainly bacitracin A, produced by spore-forming organisms belonging to the licheniformin group of the Bacillus subtilis with antibacterial activity. Bacitracin binds to C55-isoprenyl pyrophosphate, a biphosphate lipid transport molecule that carries the building blocks of the peptidoglycan bacterial cell wall. The binding interferes with the enzymatic dephosphorylation of the C55-isoprenyl pyrophosphate and prevents peptidoglycan synthesis, thereby inhibiting bacterial cell growth." @default.