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- Bae09e8a5a55c3ca4ba0c724f54dcc442 NCIT_P378 "NCI" @default.
- Bae09e8a5a55c3ca4ba0c724f54dcc442 type Axiom @default.
- Bae09e8a5a55c3ca4ba0c724f54dcc442 annotatedProperty IAO_0000115 @default.
- Bae09e8a5a55c3ca4ba0c724f54dcc442 annotatedSource NCIT_C47581 @default.
- Bae09e8a5a55c3ca4ba0c724f54dcc442 annotatedTarget "A pyrrolidine with antiepileptic activity. The exact mechanism through which levetiracetam exerts its effects is unknown but does not involve inhibitory and excitatory neurotransmitter activity. Stereoselective binding of levetiracetam was confined to synaptic plasma membranes in the central nervous system with no binding occurring in peripheral tissue. Levetiracetam inhibits burst firing without affecting normal neuronal excitability, which suggests that it may selectively prevent hyper-synchronization of epileptiform burst firing and propagation of seizure activity." @default.